Man page - clonalframe(1)
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Manual
ClonalFrame
NAMESYNOPSIS
DESCRIPTION
AUTHOR
NAME
ClonalFrame - inference of bacterial microevolution using multilocus sequence data
SYNOPSIS
ClonalFrame [OPTIONS] inputfile outputfile
DESCRIPTION
ClonalFrame identifies the clonal relationships between the members of a sample, while also estimating the chromosomal position of homologous recombination events that have disrupted the clonal inheritance.
Options:
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-x NUM |
Sets the number of iterations after burn-in (default is 50000) |
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-y NUM |
Sets the number of burn-in iterations (default is 50000) |
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-z NUM |
Sets the number of iterations between samples (default is 100) |
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-e NUM |
Sets the number of branch-swapping moves per iterations (default is so that half of the time is spent branch-swapping) |
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-m NUM |
Sets the initial value of theta to NUM (default is Watterson estimate) |
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-d NUM |
Sets the initial value of delta to NUM (default is 0.001) |
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-n NUM |
Sets the initial value of nu to NUM (default is 0.01) |
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-r NUM |
Sets the initial value of R to NUM (default is initial theta/10) |
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-M |
Do update the value of theta |
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-D |
Do not update the value of delta |
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-N |
Do not update the value of nu |
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-R |
Do not update the value of R |
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-T |
Do not update the topology |
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-A |
Do not update the ages of the nodes |
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-G |
Remove all gaps |
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-H |
Remove all gaps at non-polymorphic positions |
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-t NUM |
Indicate which initial tree to use: 0 for a null tree, 1 for a uniformly chosen coalescent tree and 2 for UPGMA tree (default) |
-w FILE
Use Newick file for initial tree
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-a NUM |
Sets the first parameter of the beta prior distribution of nu |
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-b NUM |
Sets the second parameter of the beta prior distribution of nu |
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-U |
Use uniform priors for rho, theta and delta |
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-B |
Run in BURST mode |
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-C |
Run in UPGMA mode with a site-by-site bootstrap procedure |
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-c |
Run in UPGMA mode with a fragment-by-fragment bootstrap procedure |
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-S NUM |
Sets the seed for the random number generator to NUM |
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-E NUM |
Sets the rate of exponential growth (default is 0) |
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-I |
Ignores first block in the alignment |
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-L |
Clean-up the alignment before running ClonalFrame |
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-l |
Minimum distance between two reference sites (default is 50) |
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-v |
Verbose mode |
AUTHOR
ClonalFrame was written by Xavier Didelot.
This manual page was written by Andreas Tille <tille@debian.org>, for the Debian project (but may be used by others).